What is the cause of fatty cast in nephrotic syndrome? By use of a polarizing microscope, one can see oval fat bodies and also fatty casts. These point to the nephrotic syndrome. They occur because of glomerular filtration of lipoproteins; the tubular cells that endocytose these lipoproteins then fall off into the urine.
What causes casts in urine? Casts are the result of solidification of material (protein) in the lumen of the kidney tubules, more specifically in the nephron. Once formed, these molds (or casts) of the tubule are eliminated via the urine and may be seen in the urine sedi- ment.
What causes Oval fat bodies in urine? The so called “oval fat bodies” are a common finding in the sediment of patients with higher grade proteinuria. They represent desquamated tubular epithelial cells or macrophages that are full to the brim with lipid droplets.
How edema occurs in nephrotic syndrome? The development of edema in the nephrotic syndrome has traditionally been viewed as an underfill mechanism. According to this view, urinary loss of protein results in hypoalbuminemia and decreased plasma oncotic pressure.
What is the cause of fatty cast in nephrotic syndrome? – Related Questions
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