Why is erythropoietin so difficult to detect?

Why is erythropoietin so difficult to detect? Difficulties in detection are due to the fact that EPO is a complex macromolecule, present in low con- centrations in biologic fluids, with quite a similar structure to its endogenous form, which made impossible for one to accurately identify its illicit use for a long time7,8.

Why is it hard to detect erythropoietin? “Blood doping can be achieved either via blood transfusion or EPO injections. The performance enhancing material is the blood itself, or a hormone (EPO) that is naturally produced by the body. This is why it can be so difficult to detect,” says Dr Caillaud.

How long is EPO detectable? While endogenous EPO was not decreased over the course of the study, EPO microdoses were detectable in blood and urine between 24 h and 72 h after an administration.

What are the disadvantages of erythropoietin? Erythropoietin can increase the risk of having a stroke. Signs of a stroke include: weakness or numbness in one side of your body. slurred speech or drooping of your face, mouth or eye.

EPO stands for eythropoietin.

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